AutoEditor

Overview

The AutoEditor is a tool developed at TIGR that combines the trace information with the tiling of reads within a contig in order to identify and correct sequencing errors. Note that unlike other methods for error correction, the Auto Editor will only modify a base if supporting evidence is found in the traces, thus greatly reducing the possibility of errors. In our tests the Auto Editor corrected up to 90% of the sequencing errors present in the data, leading to a corresponding reduction in the manual labor required during the finishing stages.

Publication: "Automated correction of genome sequence errors." Gajer P, Schatz M, Salzberg SL, Nucleic Acids Research, 2004. 32(2):562-9.